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Jojoba (Simmondsia chinensis)
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Jojoba/Drug Interactions:- Anti-inflammatory agentsAnti-inflammatory agents: Based on in vitro animal study, jojoba liquid wax reduced carrageenin-induced rat paw edema and prostaglandin E2 (PGE2) levels in inflammatory exudates. In a chick embryo chroioallantoic membrane model, jojoba liquid wax caused a reduction in granulation tissue formation. In rats, croton oil induced ear edema was reduced. In this model, there was also a reduction in neutrophil infiltration (decreased myeloperoxidase activity) and histopathological changes. Jojoba liquid wax reduced nitric oxide levels and tumor necrosis factor-alpha release in a lipopolysaccharide-induced inflammation rat air pouch model (3).
- Appetite suppressantsAppetite suppressants: Simmondsin isolated from jojoba meal reduces food intake in rats (16), and other studies have postulated appetite suppressing effects (9; 10; 11; 12; 13; 14; 15; 17). Consumption of jojoba meal in combination with appetite suppressants may have additive effects.
- Antilipemic agentsAntilipemic agents: The effects of jojoba oil on blood cholesterol levels have been investigated in an animal model (35).
- Mosquito repellantsMosquito repellants: A South African commercial oil containing coconut, jojoba and rapeseed oils has shown ability to act as a mosquito repellant for humans (36). Thus, use of jojoba oil in combination with other mosquito repellants may have additive effects.
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Jojoba/Herb/Supplement Interactions:- Anti-inflammatory herbsAnti-inflammatory herbs: Based on in vitro animal study, jojoba liquid wax reduced carrageenin-induced rat paw edema and prostaglandin E2 (PGE2) levels in inflammatory exudates. In a chick embryo chroioallantoic membrane model, jojoba liquid wax caused a reduction in granulation tissue formation. In rats, croton oil induced ear edema was reduced. In this model, there was also a reduction in neutrophil infiltration (decreased myeloperoxidase activity) and histopathological changes. Jojoba liquid wax reduced nitric oxide levels and tumor necrosis factor-alpha release in a lipopolysaccharide-induced inflammation rat air pouch model (3).
- AntilipemicsAntilipemics: The effects of jojoba oil on blood cholesterol levels have been investigated in an animal model (35).
- Appetite suppressantsAppetite suppressants: Simmondsin isolated from jojoba meal reduces food intake in rats (16), and other studies have postulated appetite suppressing effects (9; 10; 11; 12; 13; 14; 15; 17). Consumption of jojoba meal in combination with appetite suppressant herbs or supplements may have additive effects.
- AromatherapyAromatherapy: Jojoba oil is commonly used as a carrier oil in aromatherapy. Combinations with other carrier oils, such as almond and apricot, with the essential oils from lavender, marjoram, eucalyptus, rosemary and peppermint may offer clinical benefits (25).
- Mosquito repellantsMosquito repellants: A South African commercial oil containing coconut, jojoba and rapeseed oils has shown ability to act as a mosquito repellant (36). Thus, use of jojoba oil in combination with other mosquito repellant herbs may have additive effects.
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Jojoba/Food Interactions:- Insufficient available evidence.
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Jojoba/Lab Interactions:- Cholesterol panelCholesterol panel: The effects of jojoba oil on blood cholesterol levels have been investigated in an animal model (35).
- Fecal lipidsFecal lipids: In animals fed jojoba oil for four weeks (2.2-9% of diet), there was an increase in fecal lipid and fecal jojoba oil content (32).
- HormonesHormones: Levels of plasma growth hormone and thyroxine increased, and levels of plasma insulin-like growth factor-I and triiodothyronine decreased, in animals fed diets of 4% jojoba meal (17).
- White blood cellsWhite blood cells: In animals fed jojoba oil for four weeks (2.2-9% of diet), there was a dose related increase in white blood cell count (32).
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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